What's interesting about the recent Cheaptickets & Orbitz promo codes is that they seem to be valid for large chain hotels as well. At least in the iPhone app I was able to apply them to hotels by major chains (I tried it for example with the Novotel at Bangkok Airport). However, I did not perform the final booking, so I am not 100 % sure if the booking goes through.

I remember that in the past, these codes never worked for chain hotels.