Depends on what I have to do once I land. If I'm taking an overnight flight and am expected to be functional on arrival then sleep is the only thing that matters about being up front. The booze and the food and the lounge are relatively nothing compared to that.

That said, it also depends on what the cost differential is and who shoulders that cost. I've flown across oceans in Y many times (even in a middle seat occasionally) and lived to tell the tale. Not as comfortable as the premium cabin but it worked out fine. When I can get a bargain to fly up front I will; being flexible on routes and destinations helps on that front.