Originally Posted by manneca

Look on the Centers for Disease Control website for malaria advice. I imagine it's dependent on where you are going. Leh being in the Himalayas I doubt if it's necessary, but check.

Do not under any circumstances drink the water. Ever. Don't open your mouth in the shower. Follow the standard cautions for eating and drinking in the developing world. Wash your hands. Take pepto and Immodium (don't believe the myth that it's better to have the runs than take Immodium). Take some antibiotics for really bad cases of the runs. Are your vaccinations up to date? Are there some you may need for Leh? Check with a travel doctor. Do you have adequate health insurance that will cover you in a foreign country and includes evacuation coverage. (You might fall and break something.)

Make sure you have a visa. (I managed to forget I needed a visa once; thankfully I thought about checking just before I was going to purchase my plane tickets.)

How are you with altitude? Take it easy and breathe.

I've never been to Leh, but I have been to a number of places in northern India. It is not like traveling in Europe or the Middle East.