Conversely, if you are going by UA's definition of Middle East, which is sounds like you might be, then Turkey is in Europe. CAI is in the Middle East.
Using UA's definition, and has been talked about already, there are no *A hubs there outside of CAI. But CAI only has a few *A l/h flights eastbound. The largest number of *A l/h flights from within UA's Middle East is probably DXB. You have a few on Air China to Beijing and Chongqing, Thai to Bangkok, and SQ to Singapore. And while not longhaul, plenty of flights to India by Air India.
You've certainly peaked my interest in this, though.