The first thing I'd do is check if there is award availability on AA, United, Hawaiian, etc. Depending on where you find availability I'd apply for that cc.

For hotels it'll be a bit easier. Maui has the Hyatt, Andaz, Fairmont and Westin. Depending on where you'd like to stay apply for that cc. The Hyatt cc will get you 2 free nights anywhere and if you and your wife both get a card that'll get you 4 free nights. I've heard the Andaz is difficult to get with the free nights, but you should be fine with the Hyatt. The Fairmont will get you 2 free nights as well.