10C is a solid seat. That and 22C are my go-to seats on the all coach A321.
Per SeatGuru, 10F description:
Seat is quite uncomfortable with limited width due to in armrest tray table, under seat arm for TV and the curve of the fuselage and exit door eating in three inches. Legroom is nice but if a slightly larger person is in the middle, this is one of the worst seats on the plane.