Originally Posted by
E14 26C
Dlr direct to bank, then up a few stairs (or up an escalator and down a few seps) to the Northern line north to Moorgate, then it's a gentle flat walk around to the brewery
I agree with this. The DLR goes direct to Bank station from City Airport, taking approx. 20 minutes. It's then a short connection to the Northern Line (hint, to make it marginally easier, stay near to the rear of the DLR train for your connection at Bank, onto Moorgate). There are a few stairs at Bank for the connection but nothing bad, i.e. two flights of stairs to go up. The hotel is barely 5 minutes' walk from Moorgate station.
I don't know what your non-work plans are but you are handily close to Shoreditch if you want slightly nicer and more interesting (IMHO) options for drinking/eating/etc than staying in the City itself.