At least in my own experience, a lot of hotels these days are changing their PL rates to be a little bit higher (and it seems even more so because of the demise of bonus money) and are making Internet-only, fully-prepaid non-refundable rates available on their website which are only marginally more (10-25%) than the Priceline rates. This has at least been the case at many Wyndhams and Sheraton's I've seen.

Deals are still to be had in a lot of the larger cities with stiff competition, but I'm seeing less and less times where you can get 75% off... like the days when you could get a $40 hotel for $1 .. or 97% off!