Everything is a matter of perspective. It's a matter of how far you want to go in that perspective. Your two hour delay due to weather or MX and missing an "important meeting" is insignificant in life compared to a malnourished kid starving in Africa who's been forced to be a child soldier. There's some comedian who has a routine about how it's odd that people complain about flying because we should be amazed that you can now fly across the country in a few hours because it's a journey that used to take months or years and the people you started the journey with weren't necessarily the people you finished the journey with because people would die or be born during the journey.

What perspective one should take is of course, a matter of opinion and one which is directly and indirectly debated throughout the forum (as evidenced by frequent comments of "first world problem" in many threads).