I've flown FRA-SEA (in 4D) and SEA-FRA (in 83H) recently. I was concerned about 4D (see post #195) but was not able to find any fault with it. This is the only seat where you are guaranteed that nobody is going to step over you and you will not have to step over someone, in addition you get larger than usual foot space due to a little "island" in front of it. Other seats are ok too, even though their foot space is wedge-shaped, so you would get a bit less room than in 4D or any other "bulkhead" rows, like row 1 on the lower deck or rows 81/84 on the upper deck.

I would say that window seats are slightly better, because your foot space is a bit wider as it is next to the fuselage - especially on the upper deck where there is a little shelf running along the wall. I did not have any problems with a regular wedge-shaped space though in 83H and I'm about 6". Also, on an aisle seat you are slightly more exposed to the light of TV screens of aisle passengers ahead of you, that happened to me during return flight. Recommendation in post #196 might be relevant for you as well.

As for the noise, the noise-cancelling headphones provided by LH are highly recommended. Even if you are not listening to anything, the noise cancellation will be active as long as they are plugged in, and the effect is quite amazing. I could not hear neither the noise of the galley behind me in 4D or front bathroom on the upper deck with them on. The only complaint is that it's a bit awkward to sleep with them on.