I'm curious why you would want to us a US credit card for your local purchases in Asia? As an expat with (I assume) an above average salary in Asia you would generally have no trouble getting a couple of local credit cards straight away.

With a US credit card, since you will (I assume) be paid in local currency and make purchases in local currency, being hit for two spreads (moving your salary to US$, and the transactions being converted to US$) plus fund transfer fees in order to use a US card seems a bit daft. Points/cashback on Asian cards aren't generally quite as high as US ones, but that still wouldn't be enough to justify using US cards as far as I can see.