If it works for you, that's great. Too many negatives for me though:

- Proximity to the loos
- Passengers congregating around said loos waiting their turn
- Crew working in the galley and all the noise that entails
- Time taken to get off the aircraft unless you have one of those bonus events where they put the steps at the back
- Where boarding is not by seat row, boarding could also be longer
- Having an aircraft's worth of passengers ahead of you at immigration

For short haul in particular, being right at the back doesn't have an awful lot going for it.