I used to have a friend who was a hard-core smokers'-rights advocate who refused to fly for eleven years due to no-smoking rules.
I remember in the mid 90s that AF introduced "smoking bars"--a room on each plane behind a heavy-plastic curtain where smokers might go & light up during cruising altitude.
I also remember Smokers' Air & Freedom Air--short-lived charter airlines, one of which required PXX to buy a lifetime membership for $20 so they could call it a private club not subject to FAA commercial aviation rules.

As a non-smoker who is bothered when smoke hits my face, I ask only 2B upwind of smokers (on the ground.) I like the solution of Austrian Airlines of giving free nicotine inhalers on request: "If you're addicted to nicotine, we'll let you use it in flight, but we won't let you start a small fire in our tube at 35Kft. "

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Play the travel game 3 vacations into the future!