I have two set of Samsonite packing cubes (comes in a set of 3) and I discovered if you open the duffel fully, you can easily put the largest one vertically, one to each side. I have seven t-shirts in one of them and a vertical mouse nested in the middle, other clothing in the other. No need to do laundry for a week. Then I slotted the two halves of my Kinesis keyboard between the two clothing cubes. And topped it off with two "cylinders": a Montbell UL jacket and a Tempur Travel neckpillow. If you are pressed by the airline you can even check this 10kg duffle in. Very impressive.