Returning from a family trip, I will have a
five hour layover in PRG (inbound from KSC lands 7:50am, flight to JFK scheduled for 12:40pm on a Saturday.)

I assume our bags will be checked through to New York and we won't have to worry about them, so will this give us enough time to get out of the airport and see any of Prague or its environs?

What would be the best way to travel,
and when would we have to head back to the airport to make the return flight?

Any tips would be appreciated, especially if anyone's tried this.