My wife and I have an Eagle Creek Switchback something or other; several years old at this point. It's a nice, high quality unit (by my standards, at least). I'm comparing it to my TravelPro suiter that is approaching 10 years of loyal service.

The Eagle Creek unit holds a similar amount of stuff, and provides straps to cinch everything down and in. Its sides are not quite as rigid, however, so it is hard to tell when it is full. The daypack is a nice feature, but is made of relatively thin material (e.g., no padding for a laptop), so that would concern me as a laptop carrying vehicle. And the daypack does make the bag "illegal" as a carryon, because the main pack plus daypack is much higher than 9" when completely stuffed. We have also never used the main pack's backpack straps, so that is just extra weight and padding we haul around, albeit not much.