Ugh. I'm not quite sure what bag you're looking for (I'm too cheap to buy Tumi), but you might want to look at Eagle Creek. Some years ago when I was still young and interested in backpacking, I needed a good backpack, but wanted one that was ergonomic and wouldn't kill me. I bought an excellent Eagle Creek bag which was wonderfully ergonomically designed (it was designed especially for women). I was so happy with it that I bought a couple of other Eagle Creek products, all of which have held up great throughout the years. They're not bad looking, and they're significantly cheaper than Tumi.

Good luck!