I've had sleeping problems my entire life and was suffering jet lag/exhaustion even on domestic trips with a 1-2 hr time change. Last summer, my doctor prescribed Ambien, and it has been a miracle drug for me. I take it about 30 minutes before bed, and it helps me fall asleep, stay asleep, and wake up feeling refreshed. No groggy/knocked out feeling in the morning. I haven't experienced any side effects. I use it on a limited basis--only when I'm travelling for work and need to get up at what is 4 or 5 am to my body. I will use it later this year on a transatlantic flight to help me sleep over night (wide awake the whole time my last four flights without it).