On US-domestic itineraries, I have had really good luck paying for wifi, getting on twitter, and corresponding with @united or @deltaassist while inflight.
I have been blocked on alternate connections, ensuring that even if I don't make it, I have a seat to the destination.
However, this doesn't help you with hotels/bags/etc. At that point, you just have to get in line. The social media and telephone agents can help you rebook your flights, but they can't help you book hotels or find your bags.