wharvey --
That's an excellent question. I can't understand why anyone would do a mileage run. Yes, I know miles are worth X, and if you can earn them for Y, and Y < X, then it's a good deal.
But that neglects to factor in the amount of time, and the other things you're unable to do because you're sitting on an airplane.
IF you were completely comfortable on airplanes, and were doing the same things you'd be doing at home, that's one thing, but if you're even slightly uncomfortable, then it makes no sense to me.
Then again, I spend too much time airborne as it is...