I prefer window seating. That way one can look out to freedom and pretend that you are not stuck in the germ tube with 150 other sweating gooberheads. Do note that it is a pretty close draw up front, though.
In coach, I highly favor the window. If for no other reason, one time a suitcase fell and clobbered me on the head when seated in aisle. Almost knocked me out and hurt like a big dog.