If I need to get to a connecting flight, aisle on the closest row I can get. OK, so it is only an extra few seconds, but sometimes every second counts.
Long haul (3+ hours), aisle. Not as confining, easier to work the laptop.
Short haul, window - nice to look around. I bring my digital camera with me, and when I land I e-mail the photos to my kids. I've gotten some really good shots. I like my nighttime view of SF. On a flight out of SJC, the pilot did an extra once around for our benefit (well, that was HIS story - it is probably that he needed for some airspace to clear)
If I MUST sleep, window. I rarely sleep, as I don't sleep so much as go comatose. I have slept through a couple of landings (kudos to the pilots, I suppose!). I am also a VERY slow starter after waking up. Walking around a terminal in a fog (personal, not meteorological) isn't much fun, especially when you have to high-tail it to the opposite end of the terminal for a connecting flight (IAH and ATL come to mind)
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"I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own."