Just make sure you know expiration dates for each hotel program, and keep track of that (if you're not staying in every program you belong to at least once a year).

The last thing you want to do is sign up for a new hotel program, then forget about a previous hotel program's expiration policy, and lose more points in the previous program than you earned in the new program.

I mention this because, for example, one of your current programs is Hilton, and they expire you after just one year of no activity.