Originally Posted by
MSPeconomist
It will be more expensive than a "regular" FC ticket, but look for nonstop transcon flights with flat beds. For example, you could take DL from LAX to JFK with flat beds, and then either connect or use a car service to PA (depending somewhat on where in the state). These are generally the same seats that DL uses on its international 757s with 2-2 seating, so not direct aisle access for all. There are a few international wide body aircraft on these routes, which would be 1-2-1 seating with 100% direct aisle access and flat beds. In parts of the year, you can even find a 777 aircraft serving the LAX-JFK and vv route.
Even with flat bed, the passenger will still need pillows to keep his leg elevated. Keeping the leg elevated is the paramount concern. Even at home, just a flat bed wasn't enough. Elevation is key to comfort.