I would like to add the 380 to the list of planes I've flown (yet curiously have no desire whatsoever to fly a 330 or 340...). My favorite transcon plane is the 319/320 though, mostly because it's got a wider seat than United's 737 fleet.
Regarding turbulence, guess I'm the oddball here. The only time I can sleep on a plane is when there's a bit of "light chop." But maybe, if the 380 really is that much more quiet, it might be OK.