Yes, the main roads are excellent. It's those small roads leading to some of these hotels you need to be aware of especially driving at night time with many unexpected sink holes.

I got pulled over once by police driving from Merida to Campeche, asking for registration, licence and passport for both me and my wife. The cop also insisted my wife provide a licence but I told him she doesn't drive. He asked twice more even after I told him that, which I found pretty strange. Are they intentionally looking for trouble? I don't know. He let us go after we showed him everything we had.