Sutton Place is really great: [*]luxurious, health/fitness-pool renovated last year[*]first class location, Robson Street around the corner[*]a (british-like) old-fashioned bar, very full - but entrance priority for hotel guests on (over-) crowded evenings (often with jazz/piano)[*]a (european-like) concierge service for all your needs
many tips on what to do, where to eat (my favorites: french=Le Gavroche, steaks=Hy's Encore) have been posted already on this board. just do a search for "Vancouver".