For me, the $100 Global Entry fee was worth it after being stuck in a security screening line @ JFK for nearly 90 minutes of standing. I have a health condition which normally doesn't interfere with my life...but 90 minutes straight of standing and not moving put me (and my health) in a bad position. If I knew it was going to be THAT bad I would have at least gotten a wheelchair for the wait. I signed up for GE the following day after I recovered.

A snow storm had come and left and air travel was starting to return to normal. TSA had a single Pre-Check/Crew/Elite lane open and a single regular lane open and that was it for the whole terminal. To process probably 400-600 pax all trying to leave and of course they insisted on running everyone through the nude-o-scope (I opted out). They had plenty of people standing around to open more lanes, but they didn't. Fortunately the airline was fully aware and was holding planes, but this was causing delays throughout their network that day.