Like others have said, I completely agree that I would not drive on Saddle Road at night. I almost lost my life on that road.
Secondly, the drive up Mauna Kea can be pretty rough. The pavement does end after a certain elevation and there are no lights. The scientists do make frequent night trips up but they're quite acclimated to the elevation. Although it might sound like a good idea, I'd remain vigilent about your parties' health conditions, if you do good and just make sure everyone is okay. Given that, check the conditions or call before you head up ( check warning at
http://hokukea.soest.hawaii.edu/forecast/mko/index.cgi ).
Would I head up again? Not at night, but certainly during the day, even if I have to put up with Saddle Road. (Just to see snow in the islands

)
Aloha