Make sure not to sit in the first two rows. They have locked armrests, so you cant even create a bit more personal space by lifting them.

Be well fed before you board, food is dismal.

And do yourself a favor - take a window seat, there is so much bathroom traffic, you will go insane.

Perhaps you are lucky enough to catch a machine with Lufthansa Entertainment system on board.

Or do like many business travelers before you, ignore LH on the route.