The N65 is a fine camera. The one I have will be 2 years old in May and it has always worked flawlessly. The camera has both fully automatic and manual operation. Controls are quite intuitive, and easy to learn. In fact, I used it as a beginner also; so, I think you’ll be pleased. I have several different lenses, so I can’t specifically comment on the 75-300mm you mention. You might want to check out bhphotovideo.com to see if you can find a deal on a lens of this type. Bottom Line: Nikon SLRs are top quality, and I have never heard anything but praise from other users.
One last tip, you should consider purchasing clear (UV) filters to protect your new lens. Any camera shop will be able to help you out. That way if your camera gets into a sticky situation the cheap filer will (hopefully) save your lens from damage.
Good luck and enjoy your trip to Africa!