Seatguru is generally not very good for BA.
Have a look at this thread:
http://www.flyertalk.com/forum/briti...on-thread.html
See the wiki at the top, which summarises the prevailing views on a number of seats.
The upper deck front cabin (in which row 53 is located) is fairly small, I don't feel the flying dorm effect. I often pick 53A/K, very private and direct aisle access, but sometimes galley noise.