That's a great question. I'd love to hear the answer too.
I'd imagine it's fine for her to go with you to the Premier line, but I guess it depends on how stringent the person is manning the line?
I am going to run into the same issue shortly -- all 3 of us have tickets where we're in economy for the first segment (1.5 flight, no F availability, no big deal), and the longer segment (almost 10 hours) in F (that's what I care about

and I paid a good sum of change fees to change it when availability appeared).
I am hoping I could check in the Premier access line. Normally, I wouldn't care and don't mind checking in whichever lane, but since my flight is at some early hours at the crack of dawn (not something I'd generally go for, but ...) anyway, point is I'd like to be able to get to the airport as late as possible...so having access to the priority lane would be helpful.
If no one knows, I can post back after my trip...unless I get lucky and gets upgraded on the first segment!