I would avoid those seats, much less pay to sit in them. The plane is large. On a large plane, there is guaranteed to be at least one clueless person -- I can see him now -- who will view the middle bulkhead as a pass-through between the two aisles on the plane. Especially with a toilet in front of 6A and 6B on the port side, I can guarantee he will start stepping over you from your right.

Honestly, Y on the 330-200 is not that bad, especially coming back from Europe, where you are not trying to sleep. If you can find ABC or FGH somewhere short of the way-back, you'll be fine. Depending how open the plane looks now, you might also want to snag CDF and bet on E not filling in. Worst case: Swap F for E when E does show up.