Originally Posted by
Greg45
Being based in Berlin I have never stayed in any of the hotels here. What I can say is that I would decide about the location first and then choose the hotel. Choosing a location I would look at the part of town (e.g. Gendarmenmarkt, Potsdamer Platz, Brandenburger Tor, Zoo, Alexanderplatz) as well as the immediate "neighborhood".
Maybe try something smaller, more boutique:
http://www.das-stue.com/
http://www.hotelsteinplatz.com/
Stue is very centrally located between eat and west, but the immediate surroundings don’t offer much. Steinplatz is in the heart of old West Berlin near Zoo station.
Both those hotels look very nice...local boutique hotels that one wouldn't necessarily notice on the major online booking engines. The Stue looks particularly nice, while the Steinplatz comes in at a little more affordable. It's too bad the Steinplatz booking page is only in German.