Just adding my two cents. Have been to the Antarctic twice. First crossing of the Drake Passage was calm going down (like a lake) but on the return, couldn't get the anti-emetic into me fast enough and had a miserable time. Next time,(to Antarctic-Falklands-South Georgia Island) I took Compazine or Phenergan suppositories and some rubber finger cots to insert. These are powerful anti-emetics and tranquilizers and you will sleep, but it sure beats the alternative of barfing your way all the way back. You will need a prescription for either one. By the way, I am an M.D.