I got really drunk at a party before a long flight I had. I wasn't suppose to drink at all, but somehow one drink after another I was pretty much wasted. With the turbulence and stuff it was really tough. Luckily I was given an op-up at check-in and I asked the agent to give me the seat closest to the lavatory. I tried the barf bag, but filled it up, so I went straight to the lavatory holding the thing all filled. The FA I think figured out what was wrong with me right away and kept offering me water. I think I spend the whole flight in the lavatory throwing up. Otherwise, I don't remember much.
Any other incidents, I think was like 20 years ago.