I fly to Asia 2-3 times per year, and up till now I've always checked bags. My usual trip duration is 7-10 days. I finally decided to see if I could do a 10 day trip to Singapore with just a carry on. I bought a 22" Rimowa Salsa Deluxe, and I was surprised at how much I could actually fit in there. The hotel I was at included 2 pieces of complimentary laundry per day, so I had no problem making it thru those 10 days.

I have Global Entry, and returning back to SFO I would always just fly right on thru immigration/customs, but would always get delayed waiting for my bag to arrive. No more!