Originally Posted by
Marambio
Another, easier option is to book a weekend in a estancia off Buenos Aires. They usually have hotel pick-ups and it's much closer than any of the destinations we've mentioned in this thread.
Sounds like the best option - and much better than Colonia.
As for the others options, have you check how long the flight is to Tierra del Fuego? Iguazu would really need 2 nights to give a full day there..... still worth going even if you don't go to the Brazilian side. Mendoza is pleasant but dull, a trip to a winery or two is fun but I don't know it's worth going all the way just for that. Salta, and Cafayate, is a more spectacular location - but again you need 2 nights to make it worthwhile