<font face="Verdana, Arial, Helvetica, sans-serif" size="2">Originally posted by Family flyer:
With an airline-affiliated card, you could consolidate your mileage pursuit to one airline - the one you flew the most and had a credit card with.</font>
Ah, let's not forget about codeshare partner-related options for programs in which award redemption is allowed re: partner metal.
e.g. Let's say one's primary carrier is C, & one of their codeshare partners is Y. Furthermore, let's say that award redemption w/ miles from account Y, for flights on carrier C, are allowed. Having a credit card associated w/ mileage earning for account Y could allow one to redeem awards not only w/ carrier C (or, more accurately, w/-carrier-Y-but-on-C-metal), but also any in-common-w/-C or not-in-common-w/-C codeshare partners of Y (carrier A, etc.).
Call it a potentially flexible, backup/"CYA" plan.