LLB:
Probably could use a little more information:
1) Are you looking for a corporate card, or a personal card you can charge business expenses to? Do you have a pain threshhold with regard to annual fees?
2) What programs (besides AA) are you looking to accumulate miles/points on? Knowing which airport you fly out of would be helpful. Would you use hotel points for hotel stays, or would you convert them?
3) Regarding the types of charging you're looking to do, what kind of cards are accepted? In my case, most of my suppliers won't take AMEX or Diners.