Dennis Luwer, who lives opposite the hotel, said a hole had been blown in the side of the building.
He said: "It's been pretty intense. We just came home and saw lots of people standing outside.
"The street has been blocked off. There is a big hole in the outer wall of the Hyatt. It's about two metres high and a metre wide.
"There's a metal garage door bulged out. We can see some windows at street level also blown out."
http://www.bbc.com/news/uk-england-london-30157144
Apparently the explosion was in the kitchen area. More details in the BBC article including employee injuries.