@:-) There's nothing stopping you from programming it in, though, and running the necessary queries in the background and displaying the results all on one page, though.
I'm pretty sure whatever data sources AwardNexus uses only allow searching single city pairs at a time, but they've built an entire system around allowing you to construct super-complex queries, doing all the legwork for you, and displaying the result in a nice, easy-to-read format. EF could very well do the same if you wanted.