Update, flew 1A on 777-300 in F and was very happy with the choice of seat. First to get served, first on and off of the plane, and in every other way, basically identical to the other seats. Extremely minimal galley noise as the food preparation area is on the opposite side of the aircraft and you don't really hear the toilets as they are a bit further ahead towards the cockpit. Can't speak to traffic to the toilets as we were only 3/8 seats filled with 2 of us on the left side, but can't see that being a problem with the doors closed.
Mark