I've gotten down to packing half the clothes I need and doing laundry
I also don't bring all my skin creams. I purchase similar small sizes and use them instead.
My problem is all the computer/iphone accessories I have to bring along. My husband and I can fill a case with laptops and various i-stuff, and their cords.
One thing I never leave home without though is my extension cord, which has become the most valuable thing I pack