Maybe, maybe not. I think the cargo on the route often makes up for any seats that may or may not be sold. If the route wasn't viable there wouldn't be two 777Ws every day, there would be one A330 - there is obviously something on the route that justifies two of those every day.
I refuse to be drawn in to the MAN / LHR debate and which is better and which isn't for potential passengers out of BHX. BHX is five minutes from where I live (sometimes when I get off EK39 at 11:50 (if on time) I'm being dropped off at home by 12:20) so you can see neither of those airports is getting my business any time soon.
End of the day, only Emirates management know what is going to happen and all this 'I was speaking to a pilots wifes best friends hairdresser in the supermarket and she said that her husband had told her [insert 3 letter airport code here] is definitely going to be next for the A380'