I've only seen loud, drunk F pax on US domestic flights. I've heard and seen videos of it happens elsewhere but I haven't witnessed it. The one that sticks out in my mind is the video of some drunk Australian having to be wrestled down by 4 SQ stewards. In conversations with SQ crew it's fairly consistently reported that Australian, Indian and British flights are the heaviest drinking. I remember one cabin crew telling me he poured a bottle of black label (diluted), into a pitcher normally used for water and went around with a bucket of ice topping off whiskey on the Delhi flights.
A bottle of Krug costs US$200 in Singapore so I'm not so keen on purchasing it, however when I fly F, I pace myself, there's lots of food as well, and before I know it we're in SFO a couple of bottles down.