These don't necessarily have 50+ beers on tap, but their taps are generally devoted to good beer, and a few have an incredible bottle selection.

Zeno's Pub, State College, PA...
http://www.zenospub.com/

Bonus points from me if you can find names on their "Passport: Around the World in 80 Beers wall" for the following quotes:
"Thanks, Dad!"
"I met my husband here."
"I met my wife here."
"Cheese, Gromit, Cheese."
"Who Is John Galt?"

If you get there on a weekend, and let me know you'll be headed there, I'll even buy you a beer if I join you. If some of the old bartenders are around, you can hear stories about me!

Al's of Hampden, Enola, PA
http://alsofhampden.com/verify.php?r...t=beerlist.php

Order by number, as their beer list, displayed on flat panel TV's, is ever changing. Again, I'll buy you a drink if you let me know you'll be there.

Holy Hound Taproom, York, PA
http://holyhoundtaproom.com/http://h...ndtaproom.com/

Again, I'll buy a drink for you...

Any of the Sharp Edge locations in Pittsburgh, PA are great, but if you stop at the Creekhouse, be careful not to pass out in the bathroom!

http://sharpedgebeer.com