747 hands down. The A380 looks awkward. Nothing pretty or elegant about it. Without wanting to turn this into another Airbus versus Boeing thread, I don't really like the lines of any Airbus airplane, except the A330. No reflection on their comfort or performance. Just the design.

IMO, the 747 is an icon and will always be the Queen of the skies. Queen of the 20th century skies, at least.

I will give a nod to the 787, though. That's an awesome looking bird.