If in coach I like to sit by the wing, because any strange sounds or movements by the plane (i.e. Slight drop in altitude, speed changes) can be witnessed by flaps moving. So you know it's normal and simply the plane leveling off or beginning descent. Other than that if you don't like Xanax, take some melatonin and a glass of wine with dinner.... Sit back, relax, have a snooze, and enjoy your flight!